Tucked away at the end of Chequessett Neck Road in the National Seashore, with 456 ft. of beach frontage and direct beach access from the property, this exceptional waterfront offers 5+ acres of privacy, with sweeping panoramic views of Cape Cod Bay, Great Island, and Wellfleet Harbor from nearly every vantage point. The main residence features 3 bedrooms, 2 full baths, dramatic vaulted ceilings, a wood-burning fireplace, and expansive windows. The second floor wrap around loft adds architectural character and functionality, offering elevated views of the natural landscape and the living area below. The primary bedroom is also located on this level and opens to a private deck with stunning vistas. A third bedroom with its own private deck captures the unmatched views from the highest point of the home. The guest house offers additional space with a large bedroom, a full bath, and waterfront deck. A staircase leads to the lower level, which includes an open living area, kitchenette, and half bath. Combining privacy, coastal beauty, and design, this property offers a rare opportunity to experience one of the Cape's most spectacular waterfront locations. Seller welcomes offers for buyer concessions.